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 | | Maciej F. Boni | | Resident Scholar | |
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| | RESEARCH TOPICS | | Public Health | PROFILE |
Maciej Boni's research focuses on the public health consequences of the evolution of infectious diseases. He has studied antigenic drift in the influenza virus, a process which allows influenza to elude vaccine-induced immunity, and the evolution of antibiotic resistance in bacteria. His work analyzes the fundamental mechanisms that drive these processes so that policy can be formulated with some knowledge as to its effects on the evolution of the disease in question. In addition, Boni has contributed to the statistical theory required for identifying recombinant viruses and bacteria; these recombinant organisms are often implicated in resistance evolution and, in the case of influenza, potentially pandemic strains. His work has enabled the searching of large databases for potentially novel and dangerous disease strains.
Boni currently works with Ramanan Laxminarayan (RFF) and David L. Smith (U. Florida) on the economic and ecological challenges to developing effective malaria treatment strategies. He is a postdoctoral fellow at the Princeton Environmental Institute and has active collaborations with researchers at Penn State's Center for Infectious Disease Dynamics, the University of Chicago, Queen's University (Ontario), the University of Vigo (Spain), the Institute for Research and Development (France), and the University of Queensland (Australia).
| EDUCATION |
Ph.D. in Biological Sciences, Stanford University, 2006
M.S. in Computational Mathematics, Stanford University, 2004
A.B. in Mathematics, Princeton University, 1999
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| FEATURED PUBLICATIONS | | Homologous recombination is very rare or absent in human influenza A virus | | Boni MF, Zhou Y, Taubenberger JK, Holmes EC | | Journal of Virology | May 2008 | Vol. 82, No. 10 | pp. 4807-4811 | | | | Controlling avian influenza in chickens | | Malani A, Boni MF, Wickelgren A, Laxminarayan R | | Harvard University Seminar in Law, Economics, and Organization Research, Item #8 | April 23, 2007 | | | | Vaccination and antigenic drift in influenza | | Boni MF | | Vaccine | forthcoming | | | | An exact nonparametric method for inferring mosaic structure in sequence triplets | | Boni MF, Posada D, and Feldman MW | | Genetics | 2007 | Vol. 176 | pp.1035-1047 | | | | Dynamics and control of antibiotic resistance in structured metapopulations | | Smith DL, Boni MF, Laxminarayan R | | Disease Evolution: Models, Concepts, and Data Analyses | Zhilan Feng, Ulf Dieckmann, Simon Levin | Providence, Rhode Island: American Mathematical Society | 2006 | | | | Epidemic dynamics and antigenic evolution in a single season of influenza A. | | Boni MF, Gog JR, Andreasen V, Feldman MW | | Proceedings of the Royal Society of London B | 2006 | Vol. 273 | pp.1307-1316 | | | | Species and functional diversity of native and human-dominated plant communities | | Mayfield MM, Boni MF, Daily GC, Ackerly D | | Ecology | 2005 | Vol. 86, No. 9 | pp.2365-2372 | | | | Evolution of antibiotic resistance by human and bacterial niche construction | | Boni MF, Feldman MW | | Evolution | 2005 | Vol. 59, No. 3 | pp. 477-491 | | | | Influenza drift and epidemic size: the race between generating and escaping immunity | | Boni MF, Gog JR, Andreasen V, Christiansen FB | | Theoretical Population Biology | 2004 | Vol. 65, No. 2 | pp.179-191 | | | | Nonparametric methods for detecting recombination in sequence data | | Maciej F. Boni | | Health Research and Policy Workshop in Biostatistics | Stanford University School of Medicine | Stanford, CA | November 9, 2006 | | | | View All Related Publications |
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| NEWS | | Study: Delaying Evolution of Drug Resistance in Malaria Parasite Possible | | Thursday, September 04, 2008 | | Targeted News Service |
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