Today a new generation of food safety policy is emerging in OECD countries and international public health forums. The United States has actively contributed to the thinking and scientific researchunderlying this new generation of policy. A consensus has emerged among nations about the basic components of an effective food safety system based on modern science and management practices. In shorthand, the vision is of a farm-to-fork, risk-based, scientifically supported safety control system. This system is built on several decades of experience with risk management in national governments,particularly in U.S. environmental and occupational and consumer safety policy. This paper describes the elements of a risk-based, farm-to-fork food safety system as it is emerging in OECD countries guided by discussions through Codex Alimentarius and traces its roots in the development of risk management policy in the United States.